Rat CXCL3 ELISA Kit PicoKine®, Carrier-free

Rat CXCL3 ELISA Kit PicoKine® (96 Tests). Quantitate Rat Cxcl3 in cell culture supernatants, cell lysates, serum and plasma (heparin, EDTA). Sensitivity: 10pg/ml. The brand Picokine indicates this is a premium quality ELISA kit. Each Picokine kit delivers precise quantification, high sensitivity, and excellent reproducibility. Only our most reliable and effective kits qualify as Picokine, guaranteeing top-tier results for your assays.

Product Specifications

Background

Chemokine (C-X-C motif) ligand 3 (CXCL3) is a small cytokine belonging to the CXC chemokine family. It is mapped to 14p2 in rat. CXCL3 controls migration and adhesion of monocytes and mediates its effects on its target cell by interacting with a cell surface chemokine receptor. It has been shown that CXCL3 regulates cell autonomously the migration of the precursors of cerebellar granule neurons toward the internal layers of cerebellum, during the morphogenesis of cerebellum. CXCL3 also play fundamental roles in the development, homeostasis and it has effects on cells of the central nervous system as well as on endothelial cells involved in angiogenesis or angiostasis.

Reproducibility

<table cellpadding="3"><tr><th>Lots</th><th>Lot 1 (pg/ml)</th><th>Lot 2 (pg/ml)</th><th>Lot 3 (pg/ml)</th><th>Lot 4 (pg/ml)</th><th>Mean (pg/ml)</th><th>Standard Deviation</th><th>CV (%)</th></tr><tr><td>Sample 1</td><td>40</td><td>40</td><td>35</td><td>39</td><td>38</td><td>2.06</td><td>5.4%</td></tr><tr><td>Sample 2</td><td>190</td><td>214</td><td>187</td><td>208</td><td>199</td><td>11.49</td><td>5.7%</td></tr><tr><td>Sample 3</td><td>394</td><td>430</td><td>453</td><td>454</td><td>432</td><td>24.34</td><td>5.6%</td></tr></table>*number of samples for each test n=16.

Synonyms

C-X-C motif chemokine 3;Cytokine-induced neutrophil chemoattractant 2;CINC-2;Macrophage inflammatory protein 2-alpha/beta;MIP2-alpha/beta;Cxcl3;Cinc2;

Gene Name

C-X-C motif chemokine 3

Gene ID

171551

UniProt

Q10746

Reactivity

Rat

Cross Reactivity

There is no detectable cross-reactivity with other relevant proteins.

Immunogen

Expression system for standard: E.coli; Immunogen sequence: R33-S101

Applications

ELISA

Standard

10 ng/tube

Sample Type

cell culture supernatants, cell lysates, serum and plasma (heparin, EDTA).

Detection Range

15.6 pg/ml - 1,000 pg/ml

Sensitivity

<10 pg/ml

Function

Ligand for CXCR2 (By similarity). Has chemotactic activity for neutrophils. May play a role in inflammation and exert its effects on endothelial cells in an autocrine fashion. .

Components

Storage Conditions

Store at 4℃ for 6 months, at -20℃ for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)