Human CEACAM1/Cd66A ELISA Kit PicoKine®, Carrier-free

Human CEACAM1/Cd66A ELISA Kit PicoKine® (96 Tests). Quantitate Human CEACAM1 in cell culture supernatants, cell lysates, serum and plasma (heparin, EDTA). Sensitivity: 10pg/ml. The brand Picokine indicates this is a premium quality ELISA kit. Each Picokine kit delivers precise quantification, high sensitivity, and excellent reproducibility. Only our most reliable and effective kits qualify as Picokine, guaranteeing top-tier results for your assays.

Product Specifications

Background

CEACAM1, also known as CD66a (Cluster of Differentiation 66a), is a human glycoprotein encoded by a gene. This gene encodes a member of the carcinoembryonic antigen (CEA) gene family, which belongs to the immunoglobulin superfamily. CEACAM1 is mapped to 19q13.2 in human. The encoded protein was originally described in bile ducts of liver as biliary glycoprotein. Subsequently, it was found to be a cell-cell adhesion molecule detected on leukocytes, epithelia, and endothelia. The encoded protein mediates cell adhesion via homophilic as well as heterophilic binding to other proteins of the subgroup. Multiple cellular activities have been attributed to the encoded protein, including roles in the differentiation and arrangement of tissue three-dimensional structure, angiogenesis, apoptosis, tumor suppression, metastasis, and the modulation of innate and adaptive immune responses.

Reproducibility

<table cellpadding="3"><tr><th>Lots</th><th>Lot 1 (pg/ml)</th><th>Lot 2 (pg/ml)</th><th>Lot 3 (pg/ml)</th><th>Lot 4 (pg/ml)</th><th>Mean (pg/ml)</th><th>Standard Deviation</th><th>CV (%)</th></tr><tr><td>Sample 1</td><td>463</td><td>407</td><td>434</td><td>425</td><td>432</td><td>20.24</td><td>4.6%</td></tr><tr><td>Sample 2</td><td>2835</td><td>2793</td><td>2564</td><td>2668</td><td>2715</td><td>106.64</td><td>3.9%</td></tr><tr><td>Sample 3</td><td>9439</td><td>8061</td><td>8668</td><td>8372</td><td>8635</td><td>511.4</td><td>5.9%</td></tr></table>*number of samples for each test n=16.

Synonyms

Carcinoembryonic antigen-related cell adhesion molecule 1;Biliary glycoprotein 1;BGP-1;CD66a;CEACAM1;BGP, BGP1;

Gene Name

Carcinoembryonic antigen-related cell adhesion molecule 1

Gene ID

634

UniProt

P13688

Reactivity

Human

Cross Reactivity

There is no detectable cross-reactivity with other relevant proteins.

Immunogen

Expression system for standard: NS0; Immunogen sequence: Q35-G428

Applications

ELISA

Standard

20 ng/tube

Sample Type

cell culture supernatants, cell lysates, serum and plasma (heparin, EDTA).

Detection Range

312 pg/ml - 20,000 pg/ml

Sensitivity

<10 pg/ml

Components

Storage Conditions

Store at 4℃ for 6 months, at -20℃ for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)