Human ADAM9 ELISA Kit PicoKine®, Carrier-free

Human ADAM9 ELISA Kit PicoKine® (96 Tests). Quantitate Human ADAM9 in cell culture supernatants, serum and plasma (heparin). Sensitivity: 10pg/ml. The brand Picokine indicates this is a premium quality ELISA kit. Each Picokine kit delivers precise quantification, high sensitivity, and excellent reproducibility. Only our most reliable and effective kits qualify as Picokine, guaranteeing top-tier results for your assays.

Product Specifications

Background

Disintegrin and metalloproteinase domain-containing protein 9, also known as MCMP or MDC9 is an enzyme that in humans is encoded by the ADAM9 gene. This gene encodes a member of the ADAM ('a disintegrin and metalloproteinase') family and exhibits a number of characteristics of class III reprolysins. This gene is mapped to 8p11.22. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis.

Reproducibility

<table cellpadding="3"><tr><th>Lots</th><th>Lot 1 (pg/ml)</th><th>Lot 2 (pg/ml)</th><th>Lot 3 (pg/ml)</th><th>Lot 4 (pg/ml)</th><th>Mean (pg/ml)</th><th>Standard Deviation</th><th>CV (%)</th></tr><tr><td>Sample 1</td><td>38</td><td>41</td><td>35</td><td>42</td><td>39</td><td>2.73</td><td>7%</td></tr><tr><td>Sample 2</td><td>260</td><td>225</td><td>245</td><td>259</td><td>247</td><td>14.14</td><td>5.7%</td></tr><tr><td>Sample 3</td><td>407</td><td>428</td><td>485</td><td>443</td><td>440</td><td>28.56</td><td>6.4%</td></tr></table>*number of samples for each test n=16.

Synonyms

Disintegrin and metalloproteinase domain-containing protein 9;ADAM 9;3.4.24.-;Cellular disintegrin-related protein;Meltrin-gamma;Metalloprotease/disintegrin/cysteine-rich protein 9;Myeloma cell metalloproteinase;ADAM9;KIAA0021, MCMP, MDC9, MLTNG;

Gene Name

Disintegrin and metalloproteinase domain-containing protein 9

Gene ID

8754

UniProt

Q13443

Reactivity

Human

Cross Reactivity

There is no detectable cross-reactivity with other relevant proteins.

Immunogen

Expression system for standard: NS0; Immunogen sequence: A29-D697

Tissue Specificity

Widely expressed. Expressed in chondrocytes. Isoform 2 is highly expressed in liver and heart. .

Applications

ELISA

Standard

10 ng/tube

Sample Type

cell culture supernatants, serum and plasma (heparin).

Detection Range

15.6 pg/ml - 1,000 pg/ml

Sensitivity

<10 pg/ml

Function

Probable zinc protease. May mediate cell-cell or cell- matrix interactions. Isoform 2 displays alpha-secretase activity for APP. .

Components

Storage Conditions

Store at 4℃ for 6 months, at -20℃ for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)