Human IL-17RB ELISA Kit PicoKine®, Carrier-free

Human IL-17RB ELISA Kit PicoKine® (96 Tests). Quantitate Human IL17RB in cell culture supernatants, cell lysates, serum and plasma (heparin, EDTA). Sensitivity: 10pg/ml. The brand Picokine indicates this is a premium quality ELISA kit. Each Picokine kit delivers precise quantification, high sensitivity, and excellent reproducibility. Only our most reliable and effective kits qualify as Picokine, guaranteeing top-tier results for your assays.

Product Specifications

Background

IL17RB, also known as CRL4, is a protein that in humans is encoded by the IL17RB gene. It is located on 3p21.1. IL17RB is produced by activated T cells exhibiting proinflammatory activities. The protein encoded by this gene is a cytokine receptor. This receptor specifically binds to IL17B and IL17E (IL25), but does not bind to IL17 (A) or IL17C. This receptor has been shown to mediate the activation of NF-kappaB and the production of IL8 induced by IL17E. And it may play a role in controlling the growth and/or differentiation of hematopoietic cells.

Reproducibility

<table cellpadding="3"><tr><th>Lots</th><th>Lot 1 (pg/ml)</th><th>Lot 2 (pg/ml)</th><th>Lot 3 (pg/ml)</th><th>Lot 4 (pg/ml)</th><th>Mean (pg/ml)</th><th>Standard Deviation</th><th>CV (%)</th></tr><tr><td>Sample 1</td><td>303</td><td>331</td><td>321</td><td>324</td><td>319</td><td>10.32</td><td>3.2%</td></tr><tr><td>Sample 2</td><td>1191</td><td>1271</td><td>1261</td><td>1276</td><td>1249</td><td>34.34</td><td>2.7%</td></tr><tr><td>Sample 3</td><td>5795</td><td>5828</td><td>6134</td><td>6129</td><td>5971</td><td>160.43</td><td>2.6%</td></tr></table>*number of samples for each test n=16.

Synonyms

Interleukin-17 receptor B;IL-17 receptor B;IL-17RB;Cytokine receptor-like 4;IL-17 receptor homolog 1;IL-17Rh1;IL17Rh1;Interleukin-17B receptor;IL-17B receptor;IL17RB;CRL4, EVI27, IL17BR;UNQ2501/PRO19612;

Gene Name

Interleukin-17 receptor B

Gene ID

55540

UniProt

Q9NRM6

Reactivity

Human

Cross Reactivity

There is no detectable cross-reactivity with other relevant proteins.

Immunogen

Expression system for standard: NS0; Immunogen sequence: R18-K286

Tissue Specificity

Expressed in several endocrine tissues, mostly in fetal and adult liver, kidney, pancreas, testis, colon, brain and small intestine; not detected in peripheral blood leukocytes, lymphoid organs, and most cell lines.

Applications

ELISA

Standard

10 ng/tube

Sample Type

cell culture supernatants, cell lysates, serum and plasma (heparin, EDTA).

Detection Range

156 pg/ml - 10,000 pg/ml

Sensitivity

<10 pg/ml

Function

Receptor for the proinflammatory cytokines IL17B and IL17E. May play a role in controlling the growth and/or differentiation of hematopoietic cells. .

Components

Storage Conditions

Store at 4℃ for 6 months, at -20℃ for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)