Mouse Renin 1/Ren1 ELISA Kit PicoKine®, Carrier-free

Mouse Renin 1/Ren1 ELISA Kit PicoKine® (96 Tests). Quantitate Mouse Ren1 in cell culture supernatants, cell lysates, serum and plasma (heparin, EDTA). Sensitivity: 10pg/ml. The brand Picokine indicates this is a premium quality ELISA kit. Each Picokine kit delivers precise quantification, high sensitivity, and excellent reproducibility. Only our most reliable and effective kits qualify as Picokine, guaranteeing top-tier results for your assays.

Product Specifications

Background

Renin-1 is also known as Ren, Angiotensinogenase or Kidney rennin. It is a member of peptidase A1 family. Renin is a highly specific endopeptidase, whose only known function is to generate angiotensin I from angiotensinogen in the plasma, initiating a cascade of reactions that produce an elevation of blood pressure and increased sodium retention by the kidney. It associated to membranes via binding to ATP6AP2.

Reproducibility

<table cellpadding="3"><tr><th>Lots</th><th>Lot 1 (pg/ml)</th><th>Lot 2 (pg/ml)</th><th>Lot 3 (pg/ml)</th><th>Lot 4 (pg/ml)</th><th>Mean (pg/ml)</th><th>Standard Deviation</th><th>CV (%)</th></tr><tr><td>Sample 1</td><td>158</td><td>161</td><td>142</td><td>150</td><td>152</td><td>7.39</td><td>4.8%</td></tr><tr><td>Sample 2</td><td>449</td><td>465</td><td>437</td><td>476</td><td>456</td><td>14.9</td><td>3.2%</td></tr><tr><td>Sample 3</td><td>1246</td><td>1215</td><td>1179</td><td>1158</td><td>1199</td><td>33.7</td><td>2.8%</td></tr></table>*number of samples for each test n=16.

Synonyms

Renin-1;3.4.23.15;Angiotensinogenase;Kidney renin;Ren1;Ren, Ren-1;

Gene Name

Renin-1

Gene ID

19701

UniProt

P06281

Reactivity

Mouse

Cross Reactivity

There is no detectable cross-reactivity with other relevant proteins.

Immunogen

Expression system for standard: NS0; Immunogen sequence: S72-R402

Tissue Specificity

Kidney.

Applications

ELISA

Standard

10 ng/tube

Sample Type

cell culture supernatants, cell lysates, serum and plasma (heparin, EDTA).

Detection Range

62.5 pg/ml - 4,000 pg/ml

Sensitivity

<10 pg/ml

Function

Renin is a highly specific endopeptidase, whose only known function is to generate angiotensin I from angiotensinogen in the plasma, initiating a cascade of reactions that produce an elevation of blood pressure and increased sodium retention by the kidney.

Components

Storage Conditions

Store at 4℃ for 6 months, at -20℃ for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)