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Mouse IL-17RC ELISA Kit PicoKine®, Carrier-free

Mouse IL-17RC ELISA Kit PicoKine® (96 Tests). Quantitate Mouse Il17rc in cell culture supernatants, cell lysates, serum and plasma (heparin, EDTA). Sensitivity: 10pg/ml. The brand Picokine indicates this is a premium quality ELISA kit. Each Picokine kit delivers precise quantification, high sensitivity, and excellent reproducibility. Only our most reliable and effective kits qualify as Picokine, guaranteeing top-tier results for your assays.

Product Specifications

Background

Interleukin-17 receptor C is a protein that in humans is encoded by the IL17RC gene. By genomic sequence analysis, IL17RC gene was mapped to chromosome 3p25.3-p24.1. This gene encodes a single-pass transmembrane protein that shares limited similarity with the interleukin-17 receptor. Multiple alternatively spliced transcript variants encoding different isoforms have been detected for this gene, but the full-length nature of only three have been determined to date. The biologic activity of IL-17 is dependent on a complex composed of IL-17RA and IL-17RC, suggesting a new paradigm for understanding the interactions between the expanded family of IL-17 ligands and their receptors.

Reproducibility

<table cellpadding="3"><tr><th>Lots</th><th>Lot 1 (pg/ml)</th><th>Lot 2 (pg/ml)</th><th>Lot 3 (pg/ml)</th><th>Lot 4 (pg/ml)</th><th>Mean (pg/ml)</th><th>Standard Deviation</th><th>CV (%)</th></tr><tr><td>Sample 1</td><td>184</td><td>193</td><td>217</td><td>202</td><td>199</td><td>12.18</td><td>6.1%</td></tr><tr><td>Sample 2</td><td>1503</td><td>1674</td><td>1723</td><td>1753</td><td>1663</td><td>96.72</td><td>5.8%</td></tr><tr><td>Sample 3</td><td>5668</td><td>5483</td><td>6424</td><td>5529</td><td>5776</td><td>380.27</td><td>6.5%</td></tr></table>*number of samples for each test n=16.

Synonyms

Interleukin-17 receptor C;IL-17 receptor C;IL-17RC;Interleukin-17 receptor-like protein;IL-17RL;ZcytoR14;Il17rc;

Gene Name

Interleukin-17 receptor C

Gene ID

171095

UniProt

Q8K4C2

Reactivity

Mouse

Cross Reactivity

There is no detectable cross-reactivity with other relevant proteins.

Immunogen

Expression system for standard: NS0; Immunogen sequence: E22-R440

Applications

ELISA

Standard

10 ng/tube

Sample Type

cell culture supernatants, cell lysates, serum and plasma (heparin, EDTA).

Detection Range

156 pg/ml - 10,000 pg/ml

Sensitivity

<10 pg/ml

Components

Description|Quantity Pre-coated 96-well strip microplate|1 Standard|2 vials Biotinylated antibody (100x)|100ul Avidin-Biotin-Peroxidase Complex (100x)|100ul Sample Diluent|30ml Antibody Diluent|12ml Avidin-Biotin-Peroxidase Diluent|12ml Color Developing Reagent (TMB)|10ml Stop Solution|10ml Wash Buffer (25x)|20ml Adhesive plate sealers|4

Storage Conditions

Store at 4℃ for 6 months, at -20℃ for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)

Calculated Molecular Weight

74389 MW

Specificity

Natural and recombinant mouse IL-17RC

Anticoagulant

heparin or EDTA

Subcellular Location

Membrane ; Single-pass type I membrane protein .

Protein Name

Interleukin-17 receptor C

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