Mouse TNFRSF13C/BAFFR ELISA Kit PicoKine®, Carrier-free

Mouse TNFRSF13C/BAFFR ELISA Kit PicoKine® (96 Tests). Quantitate Mouse Tnfrsf13c in cell culture supernatants, cell lysates, serum and plasma (heparin, EDTA). Sensitivity: 10pg/ml. The brand Picokine indicates this is a premium quality ELISA kit. Each Picokine kit delivers precise quantification, high sensitivity, and excellent reproducibility. Only our most reliable and effective kits qualify as Picokine, guaranteeing top-tier results for your assays.

Product Specifications

Background

Tumor necrosis factor receptor superfamily member 13C also known as B-cell-activating factor receptor or BAFF receptor is a protein that in humans is encoded by the TNFRSF13C gene. By homology to a BAC clone, the BAFFR gene was mapped to chromosome 22q13.1-q13.31. B-cell activating factor (BAFF) enhances B-cell survival in vitro and is a regulator of the peripheral B-cell population. The protein encoded by this gene is a receptor for BAFF and is a type III transmembrane protein containing a single extracellular phenylalanine-rich domain. It is thought that this receptor is the principal receptor required for BAFF-mediated mature B-cell survival.

Reproducibility

<table cellpadding="3"><tr><th>Lots</th><th>Lot 1 (pg/ml)</th><th>Lot 2 (pg/ml)</th><th>Lot 3 (pg/ml)</th><th>Lot 4 (pg/ml)</th><th>Mean (pg/ml)</th><th>Standard Deviation</th><th>CV (%)</th></tr><tr><td>Sample 1</td><td>110</td><td>112</td><td>109</td><td>105</td><td>109</td><td>2.54</td><td>2.3%</td></tr><tr><td>Sample 2</td><td>605</td><td>673</td><td>577</td><td>616</td><td>617</td><td>34.92</td><td>5.6%</td></tr><tr><td>Sample 3</td><td>2620</td><td>2839</td><td>2527</td><td>2525</td><td>2627</td><td>127.86</td><td>4.8%</td></tr></table>*number of samples for each test n=16.

Synonyms

Tumor necrosis factor receptor superfamily member 13C;B-cell maturation defect;B-cell-activating factor receptor;BAFF receptor;BAFF-R;BLyS receptor 3;CD268;Tnfrsf13c;Baffr, Bcmd, Br3;

Gene Name

Tumor necrosis factor receptor superfamily member 13C

Gene ID

72049

UniProt

Q9D8D0

Reactivity

Mouse

Cross Reactivity

There is no detectable cross-reactivity with other relevant proteins.

Immunogen

Expression system for standard: NS0; Immunogen sequence: S10-A71

Tissue Specificity

Highly expressed in spleen and testis; detected at lower levels in lung and thymus.

Applications

ELISA

Standard

10 ng/tube

Sample Type

cell culture supernatants, cell lysates, serum and plasma (heparin, EDTA).

Detection Range

78 pg/ml - 5,000 pg/ml

Sensitivity

<10 pg/ml

Function

B-cell receptor specific for TNFSF13B/TALL1/BAFF/BLyS. Promotes the survival of mature B-cells and the B-cell response. .

Components

Storage Conditions

Store at 4℃ for 6 months, at -20℃ for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)