Human IL-17RC ELISA Kit PicoKine®, Carrier-free

Human IL-17RC ELISA Kit PicoKine® (96 Tests). Quantitate Human IL17RC in cell culture supernatants, cell lysates, serum and plasma (heparin, EDTA). Sensitivity: 15pg/ml. The brand Picokine indicates this is a premium quality ELISA kit. Each Picokine kit delivers precise quantification, high sensitivity, and excellent reproducibility. Only our most reliable and effective kits qualify as Picokine, guaranteeing top-tier results for your assays.

Product Specifications

Background

Interleukin-17 receptor C is a protein that in humans is encoded by the IL17RC gene. By genomic sequence analysis, IL17RC gene was mapped to chromosome 3p25.3-p24.1. This gene encodes a single-pass transmembrane protein that shares limited similarity with the interleukin-17 receptor. Multiple alternatively spliced transcript variants encoding different isoforms have been detected for this gene, but the full-length nature of only three have been determined to date. The biologic activity of IL-17 is dependent on a complex composed of IL-17RA and IL-17RC, suggesting a new paradigm for understanding the interactions between the expanded family of IL-17 ligands and their receptors.

Reproducibility

<table cellpadding="3"><tr><th>Lots</th><th>Lot 1 (pg/ml)</th><th>Lot 2 (pg/ml)</th><th>Lot 3 (pg/ml)</th><th>Lot 4 (pg/ml)</th><th>Mean (pg/ml)</th><th>Standard Deviation</th><th>CV (%)</th></tr><tr><td>Sample 1</td><td>343</td><td>379</td><td>386</td><td>353</td><td>365</td><td>17.78</td><td>4.8%</td></tr><tr><td>Sample 2</td><td>2996</td><td>3084</td><td>2676</td><td>2811</td><td>2891</td><td>158.82</td><td>5.4%</td></tr><tr><td>Sample 3</td><td>7791</td><td>7695</td><td>8440</td><td>8396</td><td>8080</td><td>339.55</td><td>4.2%</td></tr></table>*number of samples for each test n=16.

Synonyms

Interleukin-17 receptor C;IL-17 receptor C;IL-17RC;Interleukin-17 receptor homolog;IL17Rhom;Interleukin-17 receptor-like protein;IL-17RL;ZcytoR14;IL17RC;UNQ6118/PRO20040/PRO38901;

Gene Name

Interleukin-17 receptor C

Gene ID

84818

UniProt

Q8NAC3

Reactivity

Human

Cross Reactivity

There is no detectable cross-reactivity with other relevant proteins.

Immunogen

Expression system for standard: NS0; Immunogen sequence: L21-A454

Tissue Specificity

Expressed in brain, cartilage, colon, heart, intestine, kidney, liver, lung, muscle, placenta, and prostate. Low expression in thymus and leukocytes. Expressed (at protein level) in prostate and prostate cancer, skeletal muscle, kidney and placenta. .

Applications

ELISA

Standard

20 ng/tube

Sample Type

cell culture supernatants, cell lysates, serum and plasma (heparin, EDTA).

Detection Range

250 pg/ml - 16000 pg/ml

Sensitivity

<15 pg/ml

Components

Storage Conditions

Store at 4℃ for 6 months, at -20℃ for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)