Mouse MPO/Myeloperoxidase ELISA Kit PicoKine®, Carrier-free

Mouse MPO/Myeloperoxidase ELISA Kit PicoKine® (96 Tests). Quantitate Mouse Mpo in cell culture supernatants, cell lysates, serum and plasma (heparin, EDTA). Sensitivity: 10pg/ml. The brand Picokine indicates this is a premium quality ELISA kit. Each Picokine kit delivers precise quantification, high sensitivity, and excellent reproducibility. Only our most reliable and effective kits qualify as Picokine, guaranteeing top-tier results for your assays.

Product Specifications

Background

Myeloperoxidase (MPO) is a mammalian phagocyte hemoprotein thought to primarily mediate host defense reactions. It is abundantly expressed in neutrophils and secreted during their activation. Myeloperoxidase is part of the host defense system of human polymorphonuclear leukocytes, responsible for microbicidal activity against a wide range of organisms. It is located in the nucleus as well as in the cytoplasm. Intranuclear MPO may help to protect DNA against damage resulting from oxygen radicals produced during myeloid cell maturation and function.

Reproducibility

<table cellpadding="3"><tr><th>Lots</th><th>Lot 1 (pg/ml)</th><th>Lot 2 (pg/ml)</th><th>Lot 3 (pg/ml)</th><th>Lot 4 (pg/ml)</th><th>Mean (pg/ml)</th><th>Standard Deviation</th><th>CV (%)</th></tr><tr><td>Sample 1</td><td>354</td><td>346</td><td>367</td><td>309</td><td>344</td><td>21.55</td><td>6.2%</td></tr><tr><td>Sample 2</td><td>1809</td><td>1947</td><td>1689</td><td>1851</td><td>1824</td><td>92.61</td><td>5%</td></tr><tr><td>Sample 3</td><td>5328</td><td>4954</td><td>4733</td><td>4680</td><td>4923</td><td>255.01</td><td>5.1%</td></tr></table>*number of samples for each test n=16.

Synonyms

Myeloperoxidase;MPO;1.11.2.2;Myeloperoxidase light chain;Myeloperoxidase heavy chain;Mpo;

Gene Name

Myeloperoxidase

Gene ID

17523

UniProt

P11247

Reactivity

Mouse

Cross Reactivity

There is no detectable cross-reactivity with other relevant proteins.

Immunogen

Expression system for standard: NS0; Immunogen sequence: M16-T718

Applications

ELISA

Standard

10 ng/tube

Sample Type

cell culture supernatants, cell lysates, serum and plasma (heparin, EDTA).

Detection Range

156 pg/ml - 10,000 pg/ml

Sensitivity

<10 pg/ml

Function

Part of the host defense system of polymorphonuclear leukocytes. It is responsible for microbicidal activity against a wide range of organisms. In the stimulated PMN, MPO catalyzes the production of hypohalous acids, primarily hypochlorous acid in physiologic situations, and other toxic intermediates that greatly enhance PMN microbicidal activity (By similarity). .

Components

Storage Conditions

Store at 4℃ for 6 months, at -20℃ for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)