Human SCGB1A1/uteroglobin ELISA Kit PicoKine®, Carrier-free

Human SCGB1A1/uteroglobin ELISA Kit PicoKine® (96 Tests). Quantitate Human SCGB1A1 in cell culture supernatants, serum, plasma (heparin, EDTA) , saliva, urine and human milk. Sensitivity: 10pg/ml. The brand Picokine indicates this is a premium quality ELISA kit. Each Picokine kit delivers precise quantification, high sensitivity, and excellent reproducibility. Only our most reliable and effective kits qualify as Picokine, guaranteeing top-tier results for your assays.

Product Specifications

Background

SCGB1A1 (secretoglobin family 1A member 1) also known as Uteroglobin is a protein that in humans is encoded by the SCGB1A1 gene. SCGB1A1 is the founding member of the secretoglobin family of small, secreted, disulfide-bridged dimeric proteins found only in mammals. This protein is specifically expressed in Clara cells in the lungs. Numerous studies demonstrated that UG is a multifunctional protein with antiinflammatory/ immunomodulatory properties. It inhibits soluble phospholipase A (2) activity and binds and perhaps sequesters hydrophobic ligands such as progesterone, retinols, polychlorinated biphenyls, phospholipids, and prostaglandins. In addition to its antiinflammatory activities, UG manifests antichemotactic, antiallergic, antitumorigenic, and embryonic growth-stimulatory activities.

Reproducibility

<table cellpadding="3"><tr><th>Lots</th><th>Lot 1 (pg/ml)</th><th>Lot 2 (pg/ml)</th><th>Lot 3 (pg/ml)</th><th>Lot 4 (pg/ml)</th><th>Mean (pg/ml)</th><th>Standard Deviation</th><th>CV (%)</th></tr><tr><td>Sample 1</td><td>330</td><td>331</td><td>310</td><td>315</td><td>321</td><td>9.17</td><td>2.8%</td></tr><tr><td>Sample 2</td><td>1779</td><td>1757</td><td>1732</td><td>2013</td><td>1820</td><td>112.51</td><td>6.1%</td></tr><tr><td>Sample 3</td><td>5273</td><td>5090</td><td>5978</td><td>5483</td><td>5456</td><td>331.91</td><td>6%</td></tr></table>*number of samples for each test n=16.

Synonyms

Uteroglobin;Clara cell phospholipid-binding protein;CCPBP;Clara cells 10 kDa secretory protein;CC10;Secretoglobin family 1A member 1;Urinary protein 1;UP-1;UP1;Urine protein 1;SCGB1A1;CC10, CCSP, UGB;

Gene Name

Uteroglobin

Gene ID

7356

UniProt

P11684

Reactivity

Human

Cross Reactivity

There is no detectable cross-reactivity with other relevant proteins.

Immunogen

Expression system for standard: E.coli; Immunogen sequence: E22-N91

Tissue Specificity

Clara cells (nonciliated cells of the surface epithelium of the pulmonary airways).

Applications

ELISA

Standard

10 ng/tube

Sample Type

cell culture supernatants, serum, plasma (heparin, EDTA) , saliva, urine and human milk.

Detection Range

156 pg/ml - 10,000 pg/ml

Sensitivity

<10 pg/ml

Function

Binds phosphatidylcholine, phosphatidylinositol, polychlorinated biphenyls (PCB) and weakly progesterone, potent inhibitor of phospholipase A2.

Components

Storage Conditions

Store at 4℃ for 6 months, at -20℃ for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)