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Mouse PTX3/Pentraxin 3 ELISA Kit PicoKine®, Carrier-free

Mouse PTX3/Pentraxin 3 ELISA Kit PicoKine® (96 Tests). Quantitate Mouse Ptx3 in cell culture supernatants, serum and plasma (EDTA). Sensitivity: 10pg/ml. The brand Picokine indicates this is a premium quality ELISA kit. Each Picokine kit delivers precise quantification, high sensitivity, and excellent reproducibility. Only our most reliable and effective kits qualify as Picokine, guaranteeing top-tier results for your assays.

Product Specifications

Background

PTX3 (Pentraxin 3) is a member of the pentraxin superfamily. This super family characterized by cyclic multimeric structure. The PTX3 gene is mapped to 3q25.32. The predicted 381-amino acid PTX3 protein has homology to the pentraxin protein family. Significant levels of PTX3 were detected in plasma of neutropenic patients with systemic A. PTX3 is effective in preventing CMV infection and reactivation, as well as subsequent Aspergillus infection. PTX3 activates the classical pathway of complementactivation and facilitates pathogen recognition by macrophages and DCs.

Reproducibility

<table cellpadding="3"><tr><th>Lots</th><th>Lot 1 (pg/ml)</th><th>Lot 2 (pg/ml)</th><th>Lot 3 (pg/ml)</th><th>Lot 4 (pg/ml)</th><th>Mean (pg/ml)</th><th>Standard Deviation</th><th>CV (%)</th></tr><tr><td>Sample 1</td><td>262</td><td>259</td><td>249</td><td>272</td><td>260</td><td>8.2</td><td>3.1%</td></tr><tr><td>Sample 2</td><td>1334</td><td>1350</td><td>1444</td><td>1511</td><td>1409</td><td>71.99</td><td>5.1%</td></tr><tr><td>Sample 3</td><td>4146</td><td>4596</td><td>4000</td><td>4523</td><td>4316</td><td>250</td><td>5.7%</td></tr></table>*number of samples for each test n=16.

Synonyms

Pentraxin-related protein PTX3;Pentaxin-related protein PTX3;Tumor necrosis factor-inducible gene 14 protein;TSG-14;Ptx3;Tsg14;

Gene Name

Pentraxin-related protein PTX3

Gene ID

19288

UniProt

P48759

Reactivity

Mouse

Cross Reactivity

There is no detectable cross-reactivity with other relevant proteins.

Immunogen

Expression system for standard: NS0; Immunogen sequence: E18-S381

Applications

ELISA

Standard

10 ng/tube

Sample Type

cell culture supernatants, serum and plasma (EDTA).

Detection Range

156 pg/ml - 10,000 pg/ml

Sensitivity

<10 pg/ml

Function

Plays a role in the regulation of innate resistance to pathogens, inflammatory reactions, possibly clearance of self- components and female fertility. .

Components

Description|Quantity Pre-coated 96-well strip microplate|1 Standard|2 vials Biotinylated antibody (100x)|100ul Avidin-Biotin-Peroxidase Complex (100x)|100ul Sample Diluent|30ml Antibody Diluent|12ml Avidin-Biotin-Peroxidase Diluent|12ml Color Developing Reagent (TMB)|10ml Stop Solution|10ml Wash Buffer (25x)|20ml Adhesive plate sealers|4

Storage Conditions

Store at 4℃ for 6 months, at -20℃ for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)

Calculated Molecular Weight

41812 MW

Specificity

Natural and recombinant mouse PTX3

Anticoagulant

EDTA

Subcellular Location

Secreted.

Protein Name

Pentraxin-related protein PTX3

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