Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

Human ADAMTS13 ELISA Kit EZ-Set™ (DIY Antibody Pairs), Carrier-free

Selected Variant

EZ0927-carrier-free

Size: 5 Plates/Kit

Human ADAMTS13 ELISA Kit EZ-Set™ (DIY Antibody Pairs) (antibody pairs and standards for assay development). Quantitate Human ADAMTS13 in cell culture supernatants, serum and plasma (heparin, EDTA, citrate).

Product Specifications

Background

ADAMTS13 is a zinc-containing metalloprotease enzyme. The ADAMTS13 gene is mapped to chromosome 9q34 by genomic sequence analysis. It is reported that a metal-containing proteolytic enzyme (metalloprotease) in normal plasma cleaves the peptide bond between tyrosine at position 842 and methionine at position 843 in monomeric subunits of von Willebrand factor, thereby degrading the large multimers. And it is confirmed that the ADAMTS13 gene encodes the von Willebrand factor-cleaving protease (VWFCP). ADAMTS13 is secreted in blood and degrades large vWf multimers, decreasing their activity.

Synonyms

A disintegrin and metalloproteinase with thrombospondin motifs 13;ADAM-TS 13;ADAM-TS13;ADAMTS-13;3.4.24.87;von Willebrand factor-cleaving protease;vWF-CP;vWF-cleaving protease;ADAMTS13;C9orf8;UNQ6102/PRO20085;

Gene Name

A disintegrin and metalloproteinase with thrombospondin motifs 13

Gene ID

11093

UniProt

Q76LX8

Reactivity

Human

Cross Reactivity

There is no detectable cross-reactivity with other relevant proteins.

Immunogen

Expression system for standard: CHO; Immunogen sequence: Q34-W688

Tissue Specificity

Plasma. Expressed primarily in liver. .

Applications

ELISA

Sample Type

cell culture supernatants, serum and plasma (heparin, EDTA, citrate).

Detection Range

0.78 ng/ml - 50 ng/ml

Function

Cleaves the vWF multimers in plasma into smaller forms thereby controlling vWF-mediated platelet thrombus formation. .

Components

Description Capture Antibody Detection Antibody Avidin-Biotin-Peroxidase Complex (ABC) Lyophilized Standard|

Storage Conditions

Store at 4℃ for 6 months, at -20℃ for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)

Calculated Molecular Weight

153604 MW

Specificity

Natural and recombinant human ADAMTS13

Anticoagulant

heparin, EDTA or citrate

Subcellular Location

Secreted . Secretion enhanced by O-fucosylation of TSP type-1 repeats.

Protein Name

A disintegrin and metalloproteinase with thrombospondin motifs 13

Price

Sign In for Pricing

Frequently Asked Questions

More Discoveries

Explore Other Products

Browse additional items from our catalog

Anti-IRAK4 Antibody Picoband®, Dylight550 Conjugate
PA1942-Dylight550 100 µg

Anti-IRAK4 Antibody Picoband®, Dylight550 Conjugate

Sign In for Pricing
View Details
CD54 / ICAM-1 (15.2), CF647 conjugate, 0.1mg/mL
BNC472853-100 1x 100 µL

CD54 / ICAM-1 (15.2), CF647 conjugate, 0.1mg/mL

Sign In for Pricing
View Details
Mucin 1 / EMA / Episialin / CD227 (MUC1/845), CF405S conjugate, 0.1mg/mL
BNC040845-500 1x 500 µL

Mucin 1 / EMA / Episialin / CD227 (MUC1/845), CF405S conjugate, 0.1mg/mL

Sign In for Pricing
View Details
Lamin A/C Recombinant Rabbit Monoclonal Antibody [PSH05-20]
HA722245 100 µL

Lamin A/C Recombinant Rabbit Monoclonal Antibody [PSH05-20]

Sign In for Pricing
View Details
Anti-C18orf22/RBFA Antibody Picoband®, iFluor647 Conjugate
A13257-1-iFluor647 100 µg

Anti-C18orf22/RBFA Antibody Picoband®, iFluor647 Conjugate

Sign In for Pricing
View Details
Anti-Eotaxin 3/CCL26 Antibody Picoband®, Carrier-free
PA1451-carrier-free 100 µg/Vial

Anti-Eotaxin 3/CCL26 Antibody Picoband®, Carrier-free

Sign In for Pricing
View Details