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Anti-SPINK5 / LEKTI Rabbit Monoclonal Antibody, Carrier-free

Boster Bio Anti-SPINK5 / LEKTI Rabbit Monoclonal Antibody catalog # M03254. Tested in WB application. This antibody reacts with Human, Mouse, Rat.

Product Specifications

Synonyms

Calcium/calmodulin-dependent protein kinase type II subunit alpha;CaM kinase II subunit alpha;CaMK-II subunit alpha;2.7.11.17 ;CAMK2A;CAMKA, KIAA0968;

Gene Name

Calcium/calmodulin-dependent protein kinase type II subunit alpha

UniProt

Q9NQ38

Host

Rabbit

Reactivity

Human,Mouse,Rat

Immunogen

A synthesized peptide derived from human SPINK5 / LEKTI

Clonality

Monoclonal

Clone

Clone: 29S14

Tissue Specificity

Expressed in brain in the thalamus, in fetal and adult lung and in placenta. .

Applications

WB

Purification

Affinity-chromatography

Concentration

Actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.

Form

Liquid

Reconstitution

Restore with deionized water (or equivalent) for reconstitution volume of 1.0 mL

Function

CaM-kinase II (CAMK2) is a prominent kinase in the central nervous system that may function in long-term potentiation and neurotransmitter release. Member of the NMDAR signaling complex in excitatory synapses it may regulate NMDAR-dependent potentiation of the AMPAR and synaptic plasticity (By similarity). Phosphorylates transcription factor FOXO3 on 'Ser-298' (PubMed:23805378). Activates FOXO3 transcriptional activity (By similarity). .

Components

Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.

Storage Conditions

Store at -20℃ for one year. For short term storage and frequent use, store at 4℃ for up to one month. Avoid repeated freeze-thaw cycles.

Calculated Molecular Weight

54088 MW

Observed Molecular Weight

121 kDa

Fragment

IgG

Applications Notes

WB 1:500-1:2000

Subcellular Location

Cell junction, synapse, presynaptic cell membrane . Cell junction, synapse . Postsynaptic lipid rafts. .

Protein Name

T-cell surface glycoprotein CD3 zeta chain

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