Anti-Thrombomodulin / CD141 Rabbit Monoclonal Antibody, Carrier-free

Boster Bio Anti-Thrombomodulin / CD141 Rabbit Monoclonal Antibody catalog # M01325-2. Tested in WB, IHC, Flow Cytometry applications. This antibody reacts with Mouse, Rat.

Product Specifications

Synonyms

Thrombomodulin;TM;Fetomodulin;CD141;THBD;THRM;

Gene Name

Thrombomodulin

UniProt

P15306

Host

Rabbit

Reactivity

Mouse,Rat

Immunogen

A synthesized peptide derived from human Thrombomodulin / CD141

Clonality

Monoclonal

Clone

Clone: 28T28

Tissue Specificity

Endothelial cells are unique in synthesizing thrombomodulin.

Applications

WB,IHC,Flow Cytometry

Purification

Affinity-chromatography

Concentration

Actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.

Form

Liquid

Reconstitution

Restore with deionized water (or equivalent) for reconstitution volume of 1.0 mL

Function

Thrombomodulin is a specific endothelial cell receptor that forms a 1:1 stoichiometric complex with thrombin. This complex is responsible for the conversion of protein C to the activated protein C (protein Ca). Once evolved, protein Ca scissions the activated cofactors of the coagulation mechanism, factor Va and factor VIIIa, and thereby reduces the amount of thrombin generated.

Components

Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.

Storage Conditions

Store at -20℃ for one year. For short term storage and frequent use, store at 4℃ for up to one month. Avoid repeated freeze-thaw cycles.

Calculated Molecular Weight

60329 MW

Observed Molecular Weight

105 kDa

Fragment

IgG

Applications Notes

WB 1:500-1:2000<br>IHC 1:50-1:200<br>FC 1:50

Subcellular Location

Membrane; Single-pass type I membrane protein.

Protein Name

Glycogen synthase kinase-3 beta (gsk3b)

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