Anti-Lactate Dehydrogenase C Rabbit Monoclonal Antibody, Carrier-free

Boster Bio Anti-Lactate Dehydrogenase C Rabbit Monoclonal Antibody catalog # M08060. Tested in WB application. This antibody reacts with Human.

Product Specifications

Synonyms

Tryptase alpha/beta-1;Tryptase-1;3.4.21.59;Tryptase I;Tryptase alpha-1;TPSAB1;TPS1, TPS2, TPSB1;

Gene Name

Tryptase alpha/beta-1

UniProt

P07864

Host

Rabbit

Reactivity

Human

Immunogen

A synthesized peptide derived from human Lactate Dehydrogenase C

Clonality

Monoclonal

Clone

Clone: 28L21

Tissue Specificity

Isoform 1 and isoform 2 are expressed in lung, stomach, spleen, heart and skin; in these tissues, isoform 1 is predominant. Isoform 2 is expressed in aorta, spleen, and breast tumor, with highest levels in the endothelial cells of some blood vessels surrounding the aorta, as well as those surrounding the tumor and low levels, if any, in mast cells (at protein level). .

Applications

Purification

Affinity-chromatography

Concentration

Actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.

Form

Liquid

Reconstitution

Restore with deionized water (or equivalent) for reconstitution volume of 1.0 mL

Function

Tryptase is the major neutral protease present in mast cells and is secreted upon the coupled activation-degranulation response of this cell type. May play a role in innate immunity. Isoform 2 cleaves large substrates, such as fibronectin, more efficiently than isoform 1, but seems less efficient toward small substrates (PubMed:18854315). .