Anti-TTF1 Rabbit Monoclonal Antibody, Carrier-free

Boster Bio Anti-TTF1 Rabbit Monoclonal Antibody catalog # M01322-3. Tested in WB, IHC applications. This antibody reacts with Human, Mouse, Rat.

Product Specifications

Synonyms

Homeobox protein Nkx-2.1;Homeobox protein NK-2 homolog A;Thyroid nuclear factor 1;Thyroid transcription factor 1;TTF-1;Thyroid-specific enhancer-binding protein;T/EBP;NKX2-1 ;NKX2A, TITF1, TTF1;

Gene Name

Homeobox protein Nkx-2.1

UniProt

P43699

Host

Rabbit

Reactivity

Human,Mouse,Rat

Immunogen

A synthesized peptide derived from human TTF1

Clonality

Monoclonal

Clone

Clone: 27N58

Tissue Specificity

Thyroid and lung.

Applications

WB,IHC

Purification

Affinity-chromatography

Concentration

Actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.

Form

Liquid

Reconstitution

Restore with deionized water (or equivalent) for reconstitution volume of 1.0 mL

Function

Transcription factor that binds and activates the promoter of thyroid specific genes such as thyroglobulin, thyroperoxidase, and thyrotropin receptor. Crucial in the maintenance of the thyroid differentiation phenotype. May play a role in lung development and surfactant homeostasis. Forms a regulatory loop with GRHL2 that coordinates lung epithelial cell morphogenesis and differentiation. Activates the transcription of GNRHR and plays a role in enhancing the circadian oscillation of its gene expression. Represses the transcription of the circadian transcriptional repressor NR1D1 (By similarity). .