Anti-MVD Rabbit Monoclonal Antibody, Carrier-free

Boster Bio Anti-MVD Rabbit Monoclonal Antibody catalog # M01631. Tested in WB application. This antibody reacts with Human.

Product Specifications

Synonyms

Tryptophan 5-hydroxylase 1;1.14.16.4;Tryptophan 5-monooxygenase 1;TPH1;TPH, TPRH, TRPH;

Gene Name

Tryptophan 5-hydroxylase 1

UniProt

P53602

Host

Rabbit

Reactivity

Human

Immunogen

A synthesized peptide derived from human MVD

Clonality

Monoclonal

Clone

Clone: 27M00

Tissue Specificity

Isoform 2 seems to be less widely expressed than isoform 1.

Applications

Purification

Affinity-chromatography

Concentration

Actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.

Form

Liquid

Reconstitution

Restore with deionized water (or equivalent) for reconstitution volume of 1.0 mL

Function

t-SNARE involved in the molecular regulation of neurotransmitter release. May play an important role in the synaptic function of specific neuronal systems. Associates with proteins involved in vesicle docking and membrane fusion. Regulates plasma membrane recycling through its interaction with CENPF. Modulates the gating characteristics of the delayed rectifier voltage-dependent potassium channel KCNB1 in pancreatic beta cells. .

Components

Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.

Storage Conditions

Store at -20℃ for one year. For short term storage and frequent use, store at 4℃ for up to one month. Avoid repeated freeze-thaw cycles.

Calculated Molecular Weight

50985 MW

Observed Molecular Weight

43 kDa

Fragment

IgG

Applications Notes

WB 1:500-1:2000

Subcellular Location

Cytoplasm, perinuclear region . Cell membrane ; Lipid-anchor. Cell junction, synapse, synaptosome. Membrane association requires palmitoylation. Expressed throughout cytoplasm, concentrating at the perinuclear region. Colocalizes with KCNB1 at the cell membrane (By similarity). .