Anti-Phospho-IKB alpha (S36) Rabbit Monoclonal Antibody, Carrier-free

Boster Bio Anti-Phospho-IKB alpha (S36) Rabbit Monoclonal Antibody catalog # P01139-1. Tested in WB, Flow Cytometry applications. This antibody reacts with Human, Mouse.

Product Specifications

Phospho Site

S36

Synonyms

NF-kappa-B inhibitor alpha;I-kappa-B-alpha;IkB-alpha;IkappaBalpha;Major histocompatibility complex enhancer-binding protein MAD3;NFKBIA;IKBA, MAD3, NFKBI;

Gene Name

NF-kappa-B inhibitor alpha

UniProt

P25963

Host

Rabbit

Reactivity

Human,Mouse

Immunogen

A synthesized peptide derived from human Phospho-IKB alpha (S36)

Clonality

Monoclonal

Clone

Clone: 25N33

Tissue Specificity

Expressed ubiquitously with the most abundant expression in thymus, testis, small intestine and colon. .

Applications

WB,Flow Cytometry

Purification

Affinity-chromatography

Concentration

Actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.

Form

Liquid

Function

Inhibits the activity of dimeric NF-kappa-B/REL complexes by trapping REL dimers in the cytoplasm through masking of their nuclear localization signals. On cellular stimulation by immune and proinflammatory responses, becomes phosphorylated promoting ubiquitination and degradation, enabling the dimeric RELA to translocate to the nucleus and activate transcription. .