Anti-DBF4 Rabbit Monoclonal Antibody, Carrier-free

Boster Bio Anti-DBF4 Rabbit Monoclonal Antibody catalog # M01348. Tested in WB application. This antibody reacts with Human.

Product Specifications

Synonyms

Hepcidin;Liver-expressed antimicrobial peptide 1;LEAP-1;Putative liver tumor regressor;PLTR;Hepcidin-25;Hepc25;Hepcidin-20;Hepc20;HAMP;HEPC, LEAP1;UNQ487/PRO1003;

Gene Name

Hepcidin

UniProt

Q9UBU7

Host

Rabbit

Reactivity

Human

Immunogen

A synthesized peptide derived from human DBF4

Clonality

Monoclonal

Clone

Clone: 24D74

Tissue Specificity

Highest expression in liver and to a lesser extent in heart and brain. Low levels in lung, tonsils, salivary gland, trachea, prostate gland, adrenal gland and thyroid gland. Secreted into the urine. .

Applications

Purification

Affinity-chromatography

Concentration

Actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.

Form

Liquid

Reconstitution

Restore with deionized water (or equivalent) for reconstitution volume of 1.0 mL

Function

Liver-produced hormone that constitutes the main circulating regulator of iron absorption and distribution across tissues. Acts by promoting endocytosis and degradation of ferroportin, leading to the retention of iron in iron-exporting cells and decreased flow of iron into plasma. Controls the major flows of iron into plasma: absorption of dietary iron in the intestine, recycling of iron by macrophages, which phagocytose old erythrocytes and other cells, and mobilization of stored iron from hepatocytes (PubMed:22306005). .