Anti-IL12 p40 Rabbit Monoclonal Antibody, Carrier-free

Boster Bio Anti-IL12 p40 Rabbit Monoclonal Antibody catalog # M01152-2. Tested in WB application. This antibody reacts with Human.

Product Specifications

Synonyms

NF-kappa-B inhibitor alpha;I-kappa-B-alpha;IkB-alpha;IkappaBalpha;Major histocompatibility complex enhancer-binding protein MAD3;NFKBIA;IKBA, MAD3, NFKBI;

Gene Name

NF-kappa-B inhibitor alpha

UniProt

P29460

Host

Rabbit

Reactivity

Human

Immunogen

A synthesized peptide derived from human IL12 p40

Clonality

Monoclonal

Clone

Clone: 24I67

Tissue Specificity

Expressed in brain and skeletal muscle. .

Applications

Purification

Affinity-chromatography

Concentration

Actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.

Form

Liquid

Reconstitution

Restore with deionized water (or equivalent) for reconstitution volume of 1.0 mL

Function

Inhibits the activity of dimeric NF-kappa-B/REL complexes by trapping REL dimers in the cytoplasm through masking of their nuclear localization signals. On cellular stimulation by immune and proinflammatory responses, becomes phosphorylated promoting ubiquitination and degradation, enabling the dimeric RELA to translocate to the nucleus and activate transcription. .