Anti-FHIT Rabbit Monoclonal Antibody, Carrier-free

Boster Bio Anti-FHIT Rabbit Monoclonal Antibody catalog # M01200-3. Tested in WB application. This antibody reacts with Human, Rat.

Product Specifications

Synonyms

Vascular cell adhesion protein 1;V-CAM 1;VCAM-1;INCAM-100;CD106;VCAM1;L1CAM;

Gene Name

Vascular cell adhesion protein 1

UniProt

P49789

Host

Rabbit

Reactivity

Human,Rat

Immunogen

A synthesized peptide derived from human FHIT

Clonality

Monoclonal

Clone

Clone: 24F24

Tissue Specificity

Expressed on inflammed vascular endothelium, as well as on macrophage-like and dendritic cell types in both normal and inflammed tissue.

Applications

Purification

Affinity-chromatography

Concentration

Actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.

Form

Liquid

Reconstitution

Restore with deionized water (or equivalent) for reconstitution volume of 1.0 mL

Function

Important in cell-cell recognition. Appears to function in leukocyte-endothelial cell adhesion. Interacts with integrin alpha-4/beta-1 (ITGA4/ITGB1) on leukocytes, and mediates both adhesion and signal transduction. The VCAM1/ITGA4/ITGB1 interaction may play a pathophysiologic role both in immune responses and in leukocyte emigration to sites of inflammation.