Anti-Timeless Rabbit Monoclonal Antibody, Carrier-free

Boster Bio Anti-Timeless Rabbit Monoclonal Antibody catalog # M00831. Tested in WB, IHC, ICC/IF applications. This antibody reacts with Human.

Product Specifications

Synonyms

Prolow-density lipoprotein receptor-related protein 1;LRP-1;Alpha-2-macroglobulin receptor;A2MR;Apolipoprotein E receptor;APOER;CD91;Low-density lipoprotein receptor-related protein 1 85 kDa subunit;LRP-85;Low-density lipoprotein receptor-related protein 1 515 kDa subunit;LRP-515;Low-density lipoprotein receptor-related protein 1 intracellular domain;LRPICD;LRP1;A2MR, APR;

Gene Name

Prolow-density lipoprotein receptor-related protein 1

UniProt

Q9UNS1

Host

Rabbit

Reactivity

Human

Immunogen

A synthesized peptide derived from human Timeless

Clonality

Monoclonal

Clone

Clone: 22T48

Tissue Specificity

Most abundant in liver, brain and lung.

Applications

WB,IHC,ICC,IF

Purification

Affinity-chromatography

Concentration

Actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.

Form

Liquid

Reconstitution

Restore with deionized water (or equivalent) for reconstitution volume of 1.0 mL

Function

Endocytic receptor involved in endocytosis and in phagocytosis of apoptotic cells. Required for early embryonic development. Involved in cellular lipid homeostasis. Involved in the plasma clearance of chylomicron remnants and activated LRPAP1 (alpha 2-macroglobulin), as well as the local metabolism of complexes between plasminogen activators and their endogenous inhibitors. May modulate cellular events, such as APP metabolism, kinase-dependent intracellular signaling, neuronal calcium signaling as well as neurotransmission.