Anti-MAD3 Rabbit Monoclonal Antibody, Carrier-free

Boster Bio Anti-MAD3 Rabbit Monoclonal Antibody catalog # M11285. Tested in WB, IHC, Flow Cytometry applications. This antibody reacts with Human, Mouse, Rat.

Product Specifications

Synonyms

Histone H2B type 1-K;H2B K;HIRA-interacting protein 1;HIST1H2BK;H2BFT, HIRIP1;

Gene Name

Histone H2B type 1-K

UniProt

Q9BW11

Host

Rabbit

Reactivity

Human,Mouse,Rat

Immunogen

A synthesized peptide derived from human MAD3

Clonality

Monoclonal

Clone

Clone: 21M81

Tissue Specificity

Highly expressed in skeletal muscle, heart, liver and testis. .

Applications

WB,IHC,Flow Cytometry

Purification

Affinity-chromatography

Concentration

Actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.

Form

Liquid

Reconstitution

Restore with deionized water (or equivalent) for reconstitution volume of 1.0 mL

Function

Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.