Anti-LDHA Rabbit Monoclonal Antibody, Carrier-free

Boster Bio Anti-LDHA Rabbit Monoclonal Antibody catalog # M00825-1. Tested in WB, IHC, ICC/IF, Flow Cytometry applications. This antibody reacts with Human, Mouse, Rat.

Product Specifications

Synonyms

L-lactate dehydrogenase A chain;LDH-A;1.1.1.27;Cell proliferation-inducing gene 19 protein;LDH muscle subunit;LDH-M;Renal carcinoma antigen NY-REN-59;LDHA;PIG19;

Gene Name

L-lactate dehydrogenase A chain

UniProt

P00338

Host

Rabbit

Reactivity

Human,Mouse,Rat

Immunogen

A synthesized peptide derived from human LDHA

Clonality

Monoclonal

Clone

Clone: 21L18

Tissue Specificity

Retinal pigment epithelium specific. .

Applications

WB,IHC,ICC,IF,Flow Cytometry

Purification

Affinity-chromatography

Concentration

Actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.

Form

Liquid

Reconstitution

Restore with deionized water (or equivalent) for reconstitution volume of 1.0 mL

Function

Plays important roles in the production of 11-cis retinal and in visual pigment regeneration. The soluble form binds vitamin A (all-trans-retinol), making it available for LRAT processing to all-trans-retinyl ester. The membrane form, palmitoylated by LRAT, binds all-trans-retinyl esters, making them available for IMH (isomerohydrolase) processing to all-cis- retinol. The soluble form is regenerated by transferring its palmitoyl groups onto 11-cis-retinol, a reaction catalyzed by LRAT. The enzymatic activity is linearly dependent of the expression levels and membrane association. .