Anti-LIS1 Rabbit Monoclonal Antibody, Carrier-free

Boster Bio Anti-LIS1 Rabbit Monoclonal Antibody catalog # M01273. Tested in WB application. This antibody reacts with Human, Mouse, Rat.

Product Specifications

Synonyms

Glutaminase kidney isoform, mitochondrial;GLS;3.5.1.2;K-glutaminase;L-glutamine amidohydrolase;GLS;GLS1, KIAA0838;

Gene Name

Glutaminase kidney isoform, mitochondrial

UniProt

P43034

Host

Rabbit

Reactivity

Human,Mouse,Rat

Immunogen

A synthesized peptide derived from human LIS1

Clonality

Monoclonal

Clone

Clone: 19P48

Tissue Specificity

Isoform 1 and isoform 3 are detected in brain cortex. Isoform 3 is highly expressed in astrocytoma, ganglioglioma and ependymoma. Isoform 1 is highly expressed in brain and kidney, but not detected in liver. Isoform 3 is highly expressed in heart and pancreas, detected at lower levels in placenta, lung, pancreas and kidney, but is not detected in liver. Isoform 2 is expressed in cardiac and skeletal muscle. .

Applications

Purification

Affinity-chromatography

Concentration

Actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.

Form

Liquid

Reconstitution

Restore with deionized water (or equivalent) for reconstitution volume of 1.0 mL

Function

Catalyzes the first reaction in the primary pathway for the renal catabolism of glutamine. Plays a role in maintaining acid-base homeostasis. Regulates the levels of the neurotransmitter glutamate in the brain. Isoform 2 lacks catalytic activity.