Anti-JAK1 Rabbit Monoclonal Antibody, Carrier-free

Boster Bio Anti-JAK1 Rabbit Monoclonal Antibody catalog # M00330-1. Tested in WB application. This antibody reacts with Human, Mouse, Rat.

Product Specifications

Synonyms

Cytochrome b-245 heavy chain;1.-.-.-;CGD91-phox;Cytochrome b (558) subunit beta;Cytochrome b558 subunit beta;Heme-binding membrane glycoprotein gp91phox;NADPH oxidase 2;Neutrophil cytochrome b 91 kDa polypeptide;Superoxide-generating NADPH oxidase heavy chain subunit;gp91-1;gp91-phox;p22 phagocyte B-cytochrome;CYBB;NOX2;

Gene Name

Cytochrome b-245 heavy chain

UniProt

P23458

Host

Rabbit

Reactivity

Human,Mouse,Rat

Immunogen

A synthesized peptide derived from human JAK1

Clonality

Monoclonal

Clone

Clone: 18J08

Tissue Specificity

Detected in neutrophils (at protein level). .

Applications

Purification

Affinity-chromatography

Concentration

Actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.

Form

Liquid

Reconstitution

Restore with deionized water (or equivalent) for reconstitution volume of 1.0 mL

Function

Critical component of the membrane-bound oxidase of phagocytes that generates superoxide. It is the terminal component of a respiratory chain that transfers single electrons from cytoplasmic NADPH across the plasma membrane to molecular oxygen on the exterior. Also functions as a voltage-gated proton channel that mediates the H (+) currents of resting phagocytes. It participates in the regulation of cellular pH and is blocked by zinc.