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Acetyl- (Nle4, Asp5, D-2-Nal7, Lys10) -cyclo-α-MSH (4-10) amide

Acetyl- (Nle4, Asp5, D-2-Nal7, Lys10) -cyclo-α-MSH (4-10) amide is a potent human melanocortin 3 and 4 receptors (MC3/4R) antagonist and a partial MC5R agonist; with IC50 values of 0.23, 0.06, and 0.09 nM for human MC3R, MC4R and MC5R, respectively.

Product Specifications

Purity

≥95%

Solubility

Water: 10 mg/mL

Molecular Weight

1074.24

Notes

For research use only.

AA Sequence

Ac-{Nle}-DH-{d-Nal}-RWK (Lactam bridge: Asp2-Lys7)

Available Sizes

Frequently Asked Questions

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