Acetyl- (Nle4, Asp5, D-2-Nal7, Lys10) -cyclo-α-MSH (4-10) amide
Acetyl- (Nle4, Asp5, D-2-Nal7, Lys10) -cyclo-α-MSH (4-10) amide is a potent human melanocortin 3 and 4 receptors (MC3/4R) antagonist and a partial MC5R agonist; with IC50 values of 0.23, 0.06, and 0.09 nM for human MC3R, MC4R and MC5R, respectively.
Product Specifications
Purity
≥95%
Solubility
Water: 10 mg/mL
Molecular Weight
1074.24
Notes
For research use only.
AA Sequence
Ac-{Nle}-DH-{d-Nal}-RWK (Lactam bridge: Asp2-Lys7)
Available Sizes
Frequently Asked Questions
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