Anti-Sortilin Rabbit Monoclonal Antibody, Carrier-free

Boster Bio Anti-Sortilin Rabbit Monoclonal Antibody catalog # M01666-1. Tested in WB, IHC applications. This antibody reacts with Human, Mouse, Rat.

Product Specifications

Synonyms

Mucin-16 ;MUC-16;Ovarian cancer-related tumor marker CA125 ;CA-125 ;Ovarian carcinoma antigen CA125 ;MUC16 ;CA125 ;

Gene Name

Mucin-16

UniProt

Q99523

Host

Rabbit

Reactivity

Human,Mouse,Rat

Immunogen

A synthesized peptide derived from human Sortilin

Clonality

Monoclonal

Clone

Clone: 17S35

Tissue Specificity

Expressed in corneal and conjunctival epithelia (at protein level). Overexpressed in ovarian carcinomas and ovarian low malignant potential (LMP) tumors as compared to the expression in normal ovarian tissue and ovarian adenomas. .

Applications

WB,IHC

Purification

Affinity-chromatography

Concentration

Actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.

Form

Liquid

Reconstitution

Restore with deionized water (or equivalent) for reconstitution volume of 1.0 mL

Function

Thought to provide a protective, lubricating barrier against particles and infectious agents at mucosal surfaces. .

Components

Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.

Storage Conditions

Store at -20℃ for one year. For short term storage and frequent use, store at 4℃ for up to one month. Avoid repeated freeze-thaw cycles.

Calculated Molecular Weight

1519175 MW

Observed Molecular Weight

70,80 kDa

Fragment

IgG

Applications Notes

WB 1:500-1:2000<br>IHC 1:50-1:200

Subcellular Location

Cell membrane; Single-pass type I membrane protein. Secreted, extracellular space. May be liberated into the extracellular space following the phosphorylation of the intracellular C-terminus which induces the proteolytic cleavage and liberation of the extracellular domain.