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Anti-TMEM16A Rabbit Monoclonal Antibody, Carrier-free

Boster Bio Anti-TMEM16A Rabbit Monoclonal Antibody catalog # M00713-1. Tested in IHC, Flow Cytometry applications. This antibody reacts with Human.

Product Specifications

Synonyms

Induced myeloid leukemia cell differentiation protein Mcl-1;Bcl-2-like protein 3;Bcl2-L-3;Bcl-2-related protein EAT/mcl1;mcl1/EAT;MCL1;BCL2L3;

Gene Name

Induced myeloid leukemia cell differentiation protein Mcl-1

UniProt

Q5XXA6

Host

Rabbit

Reactivity

Human

Immunogen

A synthesized peptide derived from human TMEM16A

Clonality

Monoclonal

Clone

Clone: 17A32

Tissue Specificity

In the brain, predominantly expressed in the striatum with highest levels in the caudate and lowest in the putamen. Isoform 2 is absent from most tissues except for low levels in intestine and kidney. Highest expression of isoform 3 is found in pancreatic islets. Isoform 5 is expressed at very low levels in putamen, nucleus accumbens, prefrontal cortex, amygdala, hypothalamus and intestine. Isoform 3 is up-regulated in the middle temporal gyrus of Alzheimer disease patients while isoform 2 shows no change. .

Applications

IHC,Flow Cytometry

Purification

Affinity-chromatography

Concentration

Actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.

Form

Liquid

Reconstitution

Restore with deionized water (or equivalent) for reconstitution volume of 1.0 mL

Function

Involved in the regulation of apoptosis versus cell survival, and in the maintenance of viability but not of proliferation. Mediates its effects by interactions with a number of other regulators of apoptosis. Isoform 1 inhibits apoptosis. Isoform 2 promotes apoptosis. .

Components

Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.

Storage Conditions

Store at -20℃ for one year. For short term storage and frequent use, store at 4℃ for up to one month. Avoid repeated freeze-thaw cycles.

Calculated Molecular Weight

37337 MW

Observed Molecular Weight

37 kDa

Fragment

IgG

Applications Notes

IHC 1:50-1:2000<br>FC 1:50

Subcellular Location

Membrane ; Single-pass membrane protein . Cytoplasm. Mitochondrion. Nucleus, nucleoplasm. Cytoplasmic, associated with mitochondria.

Protein Name

T-cell surface glycoprotein CD4

Frequently Asked Questions

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