Anti-ABHD5 Monoclonal Antibody, Carrier-free

Boster Bio Anti-ABHD5 Monoclonal Antibody catalog # M03209. Tested in WB, IHC, Flow Cytometry applications. This antibody reacts with Human.

Product Specifications

Synonyms

Glutamine synthetase;GS;6.3.1.2;Glutamate decarboxylase;4.1.1.15;Glutamate--ammonia ligase;GLUL;GLNS;

Gene Name

Glutamine synthetase

UniProt

Q8WTS1

Host

Rabbit

Reactivity

Human

Immunogen

A synthesized peptide derived from human ABHD5 Lysophosphatidic acid acyltransferase which functions in phosphatidic acid biosynthesis. May regulate the cellular storage of triacylglycerol through activation of the phospholipase PNPLA2. Involved in keratinocyte differentiation.

Clonality

Monoclonal

Clone

Clone: AFHE-1

Tissue Specificity

In fetal tissues, highly expressed in brain, detectable in lung and liver, but not in kidney. In adult tissues, expressed ubiquitously in the brain, detectable in the heart, liver, spleen, thymus, prostate, testis, ovary, small intestine and colon. The type A isoforms seem to be expressed predominantly in fetal brain whereas type B isoforms are expressed abundantly in both fetal and adult brain. .

Applications

WB,IHC,Flow Cytometry

Purification

Affinity-chromatography

Concentration

Actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.

Form

Liquid

Reconstitution

Restore with deionized water (or equivalent) for reconstitution volume of 1.0 mL

Function

This enzyme has 2 functions: it catalyzes the production of glutamine and 4-aminobutanoate (gamma-aminobutyric acid, GABA), the latter in a pyridoxal phosphate-independent manner (By similarity). Essential for proliferation of fetal skin fibroblasts. .