Anti-Uroplakin3a UPK3A Monoclonal Antibody, Carrier-free

Boster Bio Anti-Uroplakin3a UPK3A Monoclonal Antibody catalog # M06534-1. Tested in IHC, Flow Cytometry applications. This antibody reacts with Human.

Product Specifications

Synonyms

Death domain-containing protein CRADD;Caspase and RIP adapter with death domain;RIP-associated protein with a death domain;CRADD;RAIDD;

Gene Name

Death domain-containing protein CRADD

UniProt

O75631

Host

Rabbit

Reactivity

Human

Immunogen

A synthesized peptide derived from human Uroplakin III Component of the asymmetric unit membrane (AUM) ; a highly specialized biomembrane elaborated by terminally differentiated urothelial cells. May play an important role in AUM-cytoskeleton interaction in terminally differentiated urothelial cells.

Clonality

Monoclonal

Clone

Clone: AFEH-21

Tissue Specificity

Constitutively expressed in most tissues, with particularly high expression in adult heart, testis, liver, skeletal muscle, fetal liver and kidney.

Applications

IHC,Flow Cytometry

Purification

Affinity-chromatography

Concentration

Actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.

Form

Liquid

Reconstitution

Restore with deionized water (or equivalent) for reconstitution volume of 1.0 mL

Function

Apoptotic adaptor molecule specific for caspase-2 and FASL/TNF receptor-interacting protein RIP. In the presence of RIP and TRADD, CRADD recruits caspase-2 to the TNFR-1 signalling complex.