Anti-MUC5B Monoclonal Antibody, Carrier-free

Boster Bio Anti-MUC5B Monoclonal Antibody catalog # M00719. Tested in WB, Flow Cytometry applications. This antibody reacts with Human.

Product Specifications

Synonyms

Apolipoprotein A-I; Apo-AI; ApoA-I; Apolipoprotein A1; Proapolipoprotein A-I; ProapoA-I; Truncated apolipoprotein A-I; Apolipoprotein A-I (1-242); APOA1

Gene Name

apolipoprotein A1

UniProt

Q9HC84

Host

Rabbit

Reactivity

Human

Immunogen

A synthesized peptide derived from human MUC5B

Clonality

Monoclonal

Clone

Clone: AFCO-13

Tissue Specificity

Major protein of plasma HDL, also found in chylomicrons. Synthesized in the liver and small intestine. The oxidized form at Met-110 and Met-136 is increased in individuals with increased risk for coronary artery disease, such as in carrier of the eNOSa/b genotype and exposure to cigarette smoking. It is also present in increased levels in aortic lesions relative to native ApoA-I and increased levels are seen with increasing severity of disease.

Applications

WB,Flow Cytometry

Purification

Affinity-chromatography

Concentration

Actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.

Form

Liquid

Reconstitution

Restore with deionized water (or equivalent) for reconstitution volume of 1.0 mL

Function

Participates in the reverse transport of cholesterol from tissues to the liver for excretion by promoting cholesterol efflux from tissues and by acting as a cofactor for the lecithin cholesterol acyltransferase (LCAT). As part of the SPAP complex, activates spermatozoa motility.