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Anti-Napsin A NAPSA Monoclonal Antibody, Carrier-free

Boster Bio Anti-Napsin A NAPSA Monoclonal Antibody catalog # M05685-2. Tested in WB, IHC, IP applications. This antibody reacts with Human.

Product Specifications

Synonyms

Keratin, type II cytoskeletal 2 epidermal;Cytokeratin-2e;CK-2e;Epithelial keratin-2e;Keratin-2 epidermis;Keratin-2e;K2e;Type-II keratin Kb2;KRT2;KRT2A, KRT2E;

Gene Name

Keratin, type II cytoskeletal 2 epidermal

UniProt

O96009

Host

Rabbit

Reactivity

Human

Immunogen

A synthesized peptide derived from human NAPSIN A May be involved in processing of pneumocyte surfactant precursors.

Clonality

Monoclonal

Clone

Clone: AFBB-14

Tissue Specificity

Expressed in the upper spinous and granular suprabasal layers of normal adult epidermal tissues from most body sites including thigh, breast nipple, foot sole, penile shaft and axilla. Not present in foreskin, squamous metaplasias and carcinomas. Expression in hypertrophic and keloid scars begins in the deepest suprabasal layer. Weakly expressed in normal gingiva and tongue, however expression is induced in benign keratoses of lingual mucosa and in mild-to-moderate oral dysplasia with orthokeratinization. .

Applications

WB,IHC,IP

Purification

Affinity-chromatography

Concentration

Actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.

Form

Liquid

Reconstitution

Restore with deionized water (or equivalent) for reconstitution volume of 1.0 mL

Function

Probably contributes to terminal cornification. Associated with keratinocyte activation, proliferation and keratinization. .

Components

Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.

Storage Conditions

Store at -20℃ for one year. For short term storage and frequent use, store at 4℃ for up to one month. Avoid repeated freeze-thaw cycles.

Calculated Molecular Weight

65433 MW

Observed Molecular Weight

160 kDa

Fragment

Rabbit IgG

Applications Notes

WB 1:1000-1:5000<br>IHC 1:50-1:200<br>IP 1:50

Subcellular Location

Cytoplasm, cytoskeleton.

Protein Name

T-cell surface glycoprotein CD3 zeta chain

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