Anti-IGHD Monoclonal Antibody, Carrier-free

Boster Bio Anti-IGHD Monoclonal Antibody catalog # M05183. Tested in WB, IHC applications. This antibody reacts with Human.

Product Specifications

Synonyms

Transcription factor 7-like 1;HMG box transcription factor 3;TCF-3;TCF7L1;TCF3;

Gene Name

Transcription factor 7-like 1

UniProt

P01880

Host

Rabbit

Reactivity

Human

Immunogen

A synthesized peptide derived from human IGHD There are two named isoforms of IGHD produced by alternative splicing, a secreted form and a single pass type I membrane protein.

Clonality

Monoclonal

Clone

Clone: AFBO-9

Tissue Specificity

Detected in hair follicles and skin keratinocytes, and at lower levels in stomach epithelium. .

Applications

WB,IHC

Purification

Affinity-chromatography

Concentration

Actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.

Form

Liquid

Reconstitution

Restore with deionized water (or equivalent) for reconstitution volume of 1.0 mL

Function

Participates in the Wnt signaling pathway. Binds to DNA and acts as a repressor in the absence of CTNNB1, and as an activator in its presence. Necessary for the terminal differentiation of epidermal cells, the formation of keratohyalin granules and the development of the barrier function of the epidermis (By similarity). Down-regulates NQO1, leading to increased mitomycin c resistance. .