Anti-Securin Monoclonal Antibody, Carrier-free

Boster Bio Anti-Securin Monoclonal Antibody catalog # M02099. Tested in WB, IHC, ICC/IF, IP, Flow Cytometry applications. This antibody reacts with Human.

Product Specifications

Synonyms

Actin-related protein 2/3 complex subunit 5;Arp2/3 complex 16 kDa subunit;p16-ARC;ARPC5;ARC16;

Gene Name

Actin-related protein 2/3 complex subunit 5

UniProt

O95997

Host

Rabbit

Reactivity

Human

Immunogen

A synthesized peptide derived from human Securin Regulatory protein, which plays a central role in chromosome stability, in the p53/TP53 pathway, and DNA repair. Probably acts by blocking the action of key proteins. During the mitosis, it blocks Separase/ESPL1 function, preventing the proteolysis of the cohesin complex and the subsequent segregation of the chromosomes.

Clonality

Monoclonal

Clone

Clone: ADFH-16

Tissue Specificity

Predominantly in urogenital tissues.

Applications

WB,IHC,ICC,IF,IP,Flow Cytometry

Purification

Affinity-chromatography

Concentration

Actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.

Form

Liquid

Reconstitution

Restore with deionized water (or equivalent) for reconstitution volume of 1.0 mL

Function

Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks.