Anti-USP13 Monoclonal Antibody, Carrier-free

Boster Bio Anti-USP13 Monoclonal Antibody catalog # M07816. Tested in WB, ICC/IF, IP, Flow Cytometry applications. This antibody reacts with Human, Mouse.

Product Specifications

Synonyms

Ubiquitin-like-conjugating enzyme ATG10;6.3.2.-;Autophagy-related protein 10;APG10-like;ATG10;APG10L;PP12616;

Gene Name

Ubiquitin-like-conjugating enzyme ATG10

UniProt

Q92995

Host

Rabbit

Reactivity

Human,Mouse

Immunogen

A synthesized peptide derived from human USP13 Mediates deubiquitination of BECN1, a key regulator of autophagy, leading to stabilize the PIK3C3/VPS34-containing complexes. Also deubiquitinates USP10, an essential regulator of p53/TP53 stability.

Clonality

Monoclonal

Clone

Clone: ADDG-21

Tissue Specificity

Brain.

Applications

WB,ICC,IF,IP,Flow Cytometry

Purification

Affinity-chromatography

Concentration

Actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.

Form

Liquid

Reconstitution

Restore with deionized water (or equivalent) for reconstitution volume of 1.0 mL

Function

E2-like enzyme involved in autophagy. Acts as an E2-like enzyme that catalyzes the conjugation of ATG12 to ATG5. ATG12 conjugation to ATG5 is required for autophagy. Likely serves as an ATG5-recognition molecule. Not involved in ATG12 conjugation to ATG3 (By similarity). Plays a role in adenovirus-mediated cell lysis. .