Anti-CD79a Monoclonal Antibody, Carrier-free

Boster Bio Anti-CD79a Monoclonal Antibody catalog # M01047-1. Tested in WB, IHC, ICC/IF, Flow Cytometry applications. This antibody reacts with Human.

Product Specifications

Synonyms

Caspase-7;CASP-7;3.4.22.60;Apoptotic protease Mch-3;Cysteine protease LICE2;Caspase-7 subunit p20;Caspase-7 subunit p11;Casp7;Lice2, Mch3;

Gene Name

Caspase-7

UniProt

P11912

Host

Rabbit

Reactivity

Human

Immunogen

A synthesized peptide derived from human CD79a Antigen binding precedes formation of the CD79A and CD79B heterodimer and subsequent activation of receptor associated kinases. CD79A is a marker for B-lineage lymphoblastic leukemia; mutations in the corresponding mb-1 gene are responsible for abnormally low levels of functional B cell receptors in some cases of chronic B-cell lymphocytic leukemia.

Clonality

Monoclonal

Clone

Clone: ADOO-3

Tissue Specificity

Highly expressed in heart, lung, liver and kidney. Low levels in spleen, skeletal muscle and testis. No expression in the brain.

Applications

WB,IHC,ICC,IF,Flow Cytometry

Purification

Affinity-chromatography

Concentration

Actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.

Form

Liquid

Reconstitution

Restore with deionized water (or equivalent) for reconstitution volume of 1.0 mL

Function

Involved in the activation cascade of caspases responsible for apoptosis execution. Cleaves and activates sterol regulatory element binding proteins (SREBPs). Overexpression promotes programmed cell death (By similarity). .

Components

Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.

Storage Conditions

Store at -20℃ for one year. For short term storage and frequent use, store at 4℃ for up to one month. Avoid repeated freeze-thaw cycles.

Calculated Molecular Weight

34061 MW

Observed Molecular Weight

17 kDa

Fragment

Rabbit IgG

Applications Notes

WB 1:1000-1:5000<br>IHC 1:50-1:200<br>ICC/IF 1:50-1:200<br>FC 1:30

Subcellular Location

Cytoplasm.

Protein Name

Glycogen synthase kinase-3 beta (gsk3b)

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