Anti-Progesterone Receptor PGR Rabbit Monoclonal Antibody, Carrier-free

Boster Bio Anti-Progesterone Receptor PGR Rabbit Monoclonal Antibody catalog # M00541-1. Tested in WB, IHC, ICC/IF, IP applications. This antibody reacts with Human.

Product Specifications

Synonyms

Progesterone receptor;PR;Nuclear receptor subfamily 3 group C member 3;PGR;NR3C3;

Gene Name

Progesterone receptor

UniProt

P06401

Host

Rabbit

Reactivity

Human

Immunogen

A synthesized peptide derived from human Progesterone Receptor

Clonality

Monoclonal

Clone

Clone: EFC-16

Tissue Specificity

Epithelial tissues and brain.

Applications

WB,IHC,ICC,IF,IP

Purification

Affinity-chromatography

Concentration

Actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.

Form

Liquid

Reconstitution

Restore with deionized water (or equivalent) for reconstitution volume of 1.0 mL

Function

The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. Progesterone receptor isoform B (PRB) is involved activation of c-SRC/MAPK signaling on hormone stimulation.

Components

Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.

Storage Conditions

Store at -20℃ for one year. For short term storage and frequent use, store at 4℃ for up to one month. Avoid repeated freeze-thaw cycles.

Calculated Molecular Weight

98981 MW

Observed Molecular Weight

54 kDa

Fragment

Rabbit IgG

Applications Notes

WB 1:1000-1:2000<br>IHC 1:50-1:200<br>ICC/IF 1:50-1:200<br>IP 1:50

Subcellular Location

Nucleus. Cytoplasm. Nucleoplasmic shuttling is both homone- and cell cycle-dependent. On hormone stimulation, retained in the cytoplasm in the G (1) and G (2)/M phases.