Anti-Integrin alpha V ITGAV Rabbit Monoclonal Antibody, Carrier-free

Boster Bio Anti-Integrin alpha V ITGAV Rabbit Monoclonal Antibody catalog # M01561. Tested in WB, IHC, ICC/IF, IP applications. This antibody reacts with Human, Mouse, Rat.

Product Specifications

Synonyms

Integrin alpha-V;Vitronectin receptor subunit alpha;CD51;Integrin alpha-V heavy chain;Integrin alpha-V light chain;ITGAV;MSK8, VNRA;

Gene Name

Integrin alpha-V

UniProt

P06756

Host

Rabbit

Reactivity

Human,Mouse,Rat

Immunogen

A synthesized peptide derived from human Integrin alpha V

Clonality

Monoclonal

Clone

Clone: ABGC-9

Tissue Specificity

Isoform BimEL, isoform BimL and isoform BimS are the predominant isoforms and are ubiquitously expressed with a tissue-specific variation. Isoform Bim-gamma is most abundantly expressed in small intestine and colon, and in lower levels in spleen, prostate, testis, heart, liver and kidney. .

Applications

WB,IHC,ICC,IF,IP

Purification

Affinity-chromatography

Concentration

Actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.

Form

Liquid

Reconstitution

Restore with deionized water (or equivalent) for reconstitution volume of 1.0 mL

Function

The alpha-V (ITGAV) integrins are receptors for vitronectin, cytotactin, fibronectin, fibrinogen, laminin, matrix metalloproteinase-2, osteopontin, osteomodulin, prothrombin, thrombospondin and vWF. They recognize the sequence R-G-D in a wide array of ligands. In case of HIV-1 infection, the interaction with extracellular viral Tat protein seems to enhance angiogenesis in Kaposi's sarcoma lesions.