Anti-Leptin Receptor LEPR Rabbit Monoclonal Antibody, Carrier-free

Boster Bio Anti-Leptin Receptor LEPR Rabbit Monoclonal Antibody catalog # M00350. Tested in WB application. This antibody reacts with Human, Mouse, Rat.

Product Specifications

Synonyms

Leptin receptor;LEP-R;HuB219;OB receptor;OB-R;CD295;LEPR;DB, OBR;

Gene Name

Leptin receptor

UniProt

P48357

Host

Rabbit

Reactivity

Human,Mouse,Rat

Immunogen

A synthesized peptide derived from human Leptin Receptor

Clonality

Monoclonal

Clone

Clone: ABDO-12

Tissue Specificity

Isoform A is expressed in fetal liver and in hematopoietic tissues and choroid plexus. In adults highest expression in heart, liver, small intestine, prostate and ovary. Low level in lung and kidney. Isoform B is highly expressed in hypothalamus.

Applications

Purification

Affinity-chromatography

Concentration

Actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.

Form

Liquid

Reconstitution

Restore with deionized water (or equivalent) for reconstitution volume of 1.0 mL

Function

Receptor for obesity factor (leptin). On ligand binding, mediates signaling through JAK2/STAT3. Involved in the regulation of fat metabolism and, in a hematopoietic pathway, required for normal lymphopoiesis. May play a role in reproduction. Can also mediate the ERK/FOS signaling pathway (By similarity). .