Anti-Integrin beta 4 ITGB4 Rabbit Monoclonal Antibody, Carrier-free

Boster Bio Anti-Integrin beta 4 ITGB4 Rabbit Monoclonal Antibody catalog # M01015. Tested in WB, IHC applications. This antibody reacts with Human, Mouse.

Product Specifications

Synonyms

Integrin beta-4;GP150;CD104;ITGB4;

Gene Name

Integrin beta-4

UniProt

P16144

Host

Rabbit

Reactivity

Human,Mouse

Immunogen

A synthesized peptide derived from human Integrin beta 4

Clonality

Monoclonal

Clone

Clone: AAFE-9

Tissue Specificity

Integrin alpha-6/beta-4 is predominantly expressed by epithelia. Isoform beta-4D is also expressed in colon and placenta. Isoform beta-4E is also expressed in epidermis, lung, duodenum, heart, spleen and stomach.

Applications

WB,IHC

Purification

Affinity-chromatography

Concentration

Actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.

Form

Liquid

Reconstitution

Restore with deionized water (or equivalent) for reconstitution volume of 1.0 mL

Function

Integrin alpha-6/beta-4 is a receptor for laminin. Plays a critical structural role in the hemidesmosome of epithelial cells. Is required for the regulation of keratinocyte polarity and motility. .

Components

Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.

Storage Conditions

Store at -20℃ for one year. For short term storage and frequent use, store at 4℃ for up to one month. Avoid repeated freeze-thaw cycles.

Calculated Molecular Weight

202167 MW

Observed Molecular Weight

240 kDa

Fragment

Rabbit IgG

Applications Notes

WB 1:500-1:2000<br>IHC 1:50-1:200

Subcellular Location

Cell membrane; Single-pass type I membrane protein. Cell membrane; Lipid-anchor. Cell junction, hemidesmosome. Colocalizes with DST at the leading edge of migrating keratinocytes.