Anti-Sonic Hedgehog SHH Rabbit Monoclonal Antibody, Carrier-free

Boster Bio Anti-Sonic Hedgehog SHH Rabbit Monoclonal Antibody catalog # M00058. Tested in WB, IHC, ICC/IF, Flow Cytometry applications. This antibody reacts with Human.

Product Specifications

Synonyms

Sonic hedgehog protein;SHH;HHG-1;Sonic hedgehog protein N-product;Sonic hedgehog protein C-product;SHH;

Gene Name

Sonic hedgehog protein

UniProt

Q15465

Host

Rabbit

Reactivity

Human

Immunogen

A synthesized peptide derived from human Sonic Hedgehog

Clonality

Monoclonal

Clone

Clone: ABE-19

Tissue Specificity

Expressed in fetal intestine, liver, lung, and kidney. Not expressed in adult tissues.

Applications

WB,IHC,ICC,IF,Flow Cytometry

Purification

Affinity-chromatography

Concentration

Actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.

Form

Liquid

Reconstitution

Restore with deionized water (or equivalent) for reconstitution volume of 1.0 mL

Function

Intercellular signal essential for a variety of patterning events during development: signal produced by the notochord that induces ventral cell fate in the neural tube and somites, and the polarizing signal for patterning of the anterior- posterior axis of the developing limb bud. Displays both floor plate- and motor neuron-inducing activity. The threshold concentration of N-product required for motor neuron induction is 5-fold lower than that required for floor plate induction. Activates the transcription of target genes by interacting with its receptor PTCH1 to prevent normal inhibition by PTCH1 on the constitutive signaling activity of SMO (By similarity). .