Anti-Cyclophilin A PPIA Rabbit Monoclonal Antibody, Carrier-free

Boster Bio Anti-Cyclophilin A PPIA Rabbit Monoclonal Antibody catalog # M01308. Tested in WB, IHC applications. This antibody reacts with Human, Mouse, Rat.

Product Specifications

Synonyms

Peptidyl-prolyl cis-trans isomerase A;PPIase A;5.2.1.8;Cyclophilin A;Cyclosporin A-binding protein;Rotamase A;Peptidyl-prolyl cis-trans isomerase A, N-terminally processed;PPIA;CYPA;

Gene Name

Peptidyl-prolyl cis-trans isomerase A

UniProt

P62937

Host

Rabbit

Reactivity

Human,Mouse,Rat

Immunogen

A synthesized peptide derived from human Cyclophilin A

Clonality

Monoclonal

Clone

Clone: AABG-16

Tissue Specificity

Expressed in primitive cells of the kidney, ureter, eye, ear and central nervous system.

Applications

WB,IHC

Purification

Affinity-chromatography

Concentration

Actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.

Form

Liquid

Reconstitution

Restore with deionized water (or equivalent) for reconstitution volume of 1.0 mL

Function

PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

Components

Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.

Storage Conditions

Store at -20℃ for one year. For short term storage and frequent use, store at 4℃ for up to one month. Avoid repeated freeze-thaw cycles.

Calculated Molecular Weight

18012 MW

Observed Molecular Weight

51-55 kDa

Fragment

Rabbit IgG

Applications Notes

WB 1:500-1:2000<br>IHC 1:50-1:200

Subcellular Location

Cytoplasm . Secreted . Secretion occurs in response to oxidative stress in vascular smooth muscle through a vesicular secretory pathway that involves actin remodeling and myosin II activation, and mediates ERK1/2 activation.