Anti-Collagen XVII Rabbit Monoclonal Antibody, Carrier-free

Boster Bio Anti-Collagen XVII Rabbit Monoclonal Antibody catalog # M03031. Tested in WB, IHC, ICC/IF, IP applications. This antibody reacts with Human, Mouse, Rat.

Product Specifications

Synonyms

Collagen alpha-1 (XVII) chain;180 kDa bullous pemphigoid antigen 2;Bullous pemphigoid antigen 2;120 kDa linear IgA disease antigen;120 kDa linear IgA dermatosis antigen;Linear IgA disease antigen 1;LAD-1;97 kDa linear IgA disease antigen;97 kDa linear IgA bullous dermatosis antigen;97 kDa LAD antigen;97-LAD;Linear IgA bullous disease antigen of 97 kDa;LABD97;COL17A1;BP180, BPAG2;

Gene Name

Collagen alpha-1(XVII) chain

UniProt

Q9UMD9

Host

Rabbit

Reactivity

Human,Mouse,Rat

Immunogen

A synthesized peptide derived from human Collagen XVII

Clonality

Monoclonal

Clone

Clone: AA-3

Tissue Specificity

Detected in skin (PubMed:8618013). In the cornea, it is detected in the epithelial basement membrane, the epithelial cells, and at a lower level in stromal cells (at protein level) (PubMed:25676728). Stratified squamous epithelia. Found in hemidesmosomes. Expressed in cornea, oral mucosa, esophagus, intestine, kidney collecting ducts, ureter, bladder, urethra and thymus but is absent in lung, blood vessels, skeletal muscle and nerves. .

Applications

WB,IHC,ICC,IF,IP

Purification

Affinity-chromatography

Concentration

Actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.

Form

Liquid

Reconstitution

Restore with deionized water (or equivalent) for reconstitution volume of 1.0 mL

Function

May play a role in the integrity of hemidesmosome and the attachment of basal keratinocytes to the underlying basement membrane.

Components

Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.

Storage Conditions

Store at -20℃ for one year. For short term storage and frequent use, store at 4℃ for up to one month. Avoid repeated freeze-thaw cycles.

Calculated Molecular Weight

150419 MW

Observed Molecular Weight

56 kDa

Fragment

Rabbit IgG

Applications Notes

WB 1:500-1:2000<br>IHC 1:50-1:200<br>ICC/IF 1:50-1:200<br>IP 1:30

Subcellular Location

Cell junction, hemidesmosome. Membrane; Single-pass type II membrane protein. Localized along the plasma membrane of the hemidesmosome.

Protein Name

T-cell surface glycoprotein CD3 zeta chain

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