Anti-14-3-3 sigma SFN Rabbit Monoclonal Antibody, Carrier-free

Boster Bio Anti-14-3-3 sigma SFN Rabbit Monoclonal Antibody catalog # M01127. Tested in WB, IHC applications. This antibody reacts with Human, Rat.

Product Specifications

Synonyms

14-3-3 protein sigma;Epithelial cell marker protein 1;Stratifin;SFN;HME1;

Gene Name

14-3-3 protein sigma

UniProt

P31947

Host

Rabbit

Reactivity

Human,Rat

Immunogen

A synthesized peptide derived from human 14-3-3 sigma

Clonality

Monoclonal

Clone

Clone: HBB-19

Tissue Specificity

Present mainly in tissues enriched in stratified squamous keratinizing epithelium.

Applications

WB,IHC

Purification

Affinity-chromatography

Concentration

Actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.

Form

Liquid

Reconstitution

Restore with deionized water (or equivalent) for reconstitution volume of 1.0 mL

Function

Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner. When bound to KRT17, regulates protein synthesis and epithelial cell growth by stimulating Akt/mTOR pathway. May also regulate MDM2 autoubiquitination and degradation and thereby activate p53/TP53. .