Anti-Galectin 3 LGALS3 Rabbit Monoclonal Antibody, Carrier-free

Boster Bio Anti-Galectin 3 LGALS3 Rabbit Monoclonal Antibody catalog # M00621. Tested in WB, ICC/IF, Flow Cytometry applications. This antibody reacts with Human, Rat.

Product Specifications

Synonyms

Galectin-3;Gal-3;35 kDa lectin;Carbohydrate-binding protein 35;CBP 35;Galactose-specific lectin 3;Galactoside-binding protein;GALBP;IgE-binding protein;L-31;Laminin-binding protein;Lectin L-29;Mac-2 antigen;LGALS3;MAC2;

Gene Name

Galectin-3

UniProt

P17931

Host

Rabbit

Reactivity

Human,Rat

Immunogen

A synthesized peptide derived from human Galectin 3

Clonality

Monoclonal

Clone

Clone: AOIE-12

Tissue Specificity

A major expression is found in the colonic epithelium. It is also abundant in the activated macrophages. Expressed in fetal membranes. .

Applications

WB,ICC,IF,Flow Cytometry

Purification

Affinity-chromatography

Concentration

Actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.

Form

Liquid

Reconstitution

Restore with deionized water (or equivalent) for reconstitution volume of 1.0 mL

Function

Galactose-specific lectin which binds IgE. May mediate with the alpha-3, beta-1 integrin the stimulation by CSPG4 of endothelial cells migration. Together with DMBT1, required for terminal differentiation of columnar epithelial cells during early embryogenesis (By similarity). In the nucleus: acts as a pre-mRNA splicing factor. Involved in acute inflammatory responses including neutrophil activation and adhesion, chemoattraction of monocytes macrophages, opsonization of apoptotic neutrophils, and activation of mast cells. .