Anti-ERR alpha Rabbit Monoclonal Antibody, Carrier-free

Boster Bio Anti-ERR alpha Rabbit Monoclonal Antibody catalog # M03339. Tested in WB, IP, Flow Cytometry applications. This antibody reacts with Human, Mouse, Rat.

Product Specifications

Synonyms

Steroid hormone receptor ERR1;Estrogen receptor-like 1;Estrogen-related receptor alpha;ERR-alpha;Nuclear receptor subfamily 3 group B member 1;ESRRA;ERR1, ESRL1, NR3B1;

Gene Name

Steroid hormone receptor ERR1

UniProt

P11474

Host

Rabbit

Reactivity

Human,Mouse,Rat

Immunogen

A synthesized peptide derived from human ERR alpha

Clonality

Monoclonal

Clone

Clone: EIO-5

Tissue Specificity

Visceral organs specific expression. Strong expression was found in liver, kidney and intestine followed by spleen and to a lesser extent the adrenals.

Applications

WB,IP,Flow Cytometry

Purification

Affinity-chromatography

Concentration

Actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.

Form

Liquid

Reconstitution

Restore with deionized water (or equivalent) for reconstitution volume of 1.0 mL

Function

Binds to an ERR-alpha response element (ERRE) containing a single consensus half-site, 5'-TNAAGGTCA-3'. Can bind to the medium-chain acyl coenzyme A dehydrogenase (MCAD) response element NRRE-1 and may act as an important regulator of MCAD promoter. Binds to the C1 region of the lactoferrin gene promoter. Requires dimerization and the coactivator, PGC-1A, for full activity. The ERRalpha/PGC1alpha complex is a regulator of energy metabolism. Induces the expression of PERM1 in the skeletal muscle. .