Anti-Cyclin H Rabbit Monoclonal Antibody, Carrier-free

Boster Bio Anti-Cyclin H Rabbit Monoclonal Antibody catalog # M03013. Tested in WB, IHC, ICC/IF, IP, Flow Cytometry applications. This antibody reacts with Human, Mouse.

Product Specifications

Synonyms

Cyclin-H;MO15-associated protein;p34;p37;CCNH;

Gene Name

Cyclin-H

UniProt

P51946

Host

Rabbit

Reactivity

Human,Mouse

Immunogen

A synthesized peptide derived from human Cyclin H

Clonality

Monoclonal

Clone

Clone: GII-3

Tissue Specificity

Activated T-lymphocytes.

Applications

WB,IHC,ICC,IF,IP,Flow Cytometry

Purification

Affinity-chromatography

Concentration

Actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.

Form

Liquid

Reconstitution

Restore with deionized water (or equivalent) for reconstitution volume of 1.0 mL

Function

Regulates CDK7, the catalytic subunit of the CDK- activating kinase (CAK) enzymatic complex. CAK activates the cyclin-associated kinases CDK1, CDK2, CDK4 and CDK6 by threonine phosphorylation. CAK complexed to the core-TFIIH basal transcription factor activates RNA polymerase II by serine phosphorylation of the repetitive C-terminal domain (CTD) of its large subunit (POLR2A), allowing its escape from the promoter and elongation of the transcripts. Involved in cell cycle control and in RNA transcription by RNA polymerase II. Its expression and activity are constant throughout the cell cycle. .