Anti-NMDAR1 GRIN1 Rabbit Monoclonal Antibody, Carrier-free

Boster Bio Anti-NMDAR1 GRIN1 Rabbit Monoclonal Antibody catalog # M01808. Tested in WB application. This antibody reacts with Human, Mouse, Rat.

Product Specifications

Synonyms

Glutamate receptor ionotropic, NMDA 1;GluN1;Glutamate [NMDA] receptor subunit zeta-1;N-methyl-D-aspartate receptor subunit NR1;NMD-R1;GRIN1;NMDAR1;

Gene Name

Glutamate receptor ionotropic, NMDA 1

UniProt

Q05586

Host

Rabbit

Reactivity

Human,Mouse,Rat

Immunogen

A synthesized peptide derived from human NMDAR1

Clonality

Monoclonal

Clone

Clone: AAHF-7

Tissue Specificity

Expressed in brain and lymphoblast.

Applications

Purification

Affinity-chromatography

Concentration

Actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.

Form

Liquid

Reconstitution

Restore with deionized water (or equivalent) for reconstitution volume of 1.0 mL

Function

NMDA receptor subtype of glutamate-gated ion channels with high calcium permeability and voltage-dependent sensitivity to magnesium. Mediated by glycine. This protein plays a key role in synaptic plasticity, synaptogenesis, excitotoxicity, memory acquisition and learning. It mediates neuronal functions in glutamate neurotransmission. Is involved in the cell surface targeting of NMDA receptors (By similarity). .

Components

Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.

Storage Conditions

Store at -20℃ for one year. For short term storage and frequent use, store at 4℃ for up to one month. Avoid repeated freeze-thaw cycles.

Calculated Molecular Weight

105373 MW

Observed Molecular Weight

42 kDa

Fragment

Rabbit IgG

Applications Notes

WB 1:500-1:2000

Subcellular Location

Cell membrane ; Multi-pass membrane protein . Cell junction, synapse, postsynaptic cell membrane . Cell junction, synapse, postsynaptic cell membrane, postsynaptic density . Enriched in postsynaptic plasma membrane and postsynaptic densities. .